TCM apitherapy and rheumatoid

Bee products for the treatment of a bee venom (a) the mechanism of bee venom treatment contains bee venom peptides and enzymes and other active ingredients that have a direct and indirect effects of anti-inflammatory and analgesic; regulating immunity, enhance the immune inhibitory effects; improvement of blood circulation, increase peripheral blood supply, enhance the physiological functions of the liver and kidney and brain and its local Meridian and physical effects. Mainly anti-inflammatory analgesic and immune regulation two. From a TCM standpoint, bee venom into the human body, capable of activating detumescence pain, tongjing, activating, expelling. In addition, the bee has point punched into the acupuncture meridians. mechanical stimulation and pharmacological effects of bee venom, bee sting after Rainbow swelling reactions, there is a similar treatment effect of temperature and stir-frying. Therefore, bee-treatment with a needle, Wen Zhi, a variety of drug therapy. Is incomparable to other methods.

Since the 18th century, about the bee venom treatment of rheumatic diseases are common, the report has not yet been seen in a negative effect on rheumatic diseases bee venom's width from the robust reporting, Rimsky (1864) published the first article about the bee venom treatment of rheumatic diseases, many of the papers relating to incurable rheumatism patients are from apitherapy has been recovered. Then, Gandalf • ters (rudolph Tertsch, 1912) released a few more clinical report, treatment of rheumatism patients 666 cases, 554 cases recovered 99 cases better, only 17 cases did not reduce, then there are two kinds of patients is not complete treatment of the patient. United States Broadman (J • Broadman, 1962) monograph the bee venom — arthritis and rheumatism natural treatment agent and France Forrest Theil (F.Forestier, 1984) published a bee venom for rheumatic diseases — 1600 cases of papers, reaffirmed the bee venom on rheumatic diseases and associated disease.

Bee venom treatment of rheumatic diseases, rheumatoid arthritis with a long history. United States Charles • El Stolac, introducing his 50 years of experience in apitherapy, said: the bee venom treatment of rheumatic diseases, rheumatoid arthritis has three main advantages: the first completely reliable; the second significant efficacy; third spend less. Concisely. On extremely difficult to cure rheumatoid arthritis using honey bee venom treatment without side effects and long-term effects, such as with physical therapy, you can get unexpected clinical results: alesker (1964) reported use of bee venom treatment of rheumatoid arthritis 310 cases, 112 cases with hormones, 59 patients treated by salicylic acid sodium for observation, see table (18-3), as can be seen from the table, the five methods to bee venom and hormone therapy method works best. 1 the 1905 patients — 5 years of follow-up, prove that the long-term effects of bee venom than hormone or salicylic acid and sodium. Money in introducing the anatase Soviet General bee venom medical clinic, said that the bee venom on infectious arthritis, rheumatism, spondylitis. Use of bee venom treatment 500 patients, at first only with 1 day after the bee, and gradually increased to 15, 20, 30, only bee, most patients receive a total of 300 to 500 only bee. Interrupt 1 and a half months to two months after receiving treatment, 90 per cent of patients is good and satisfied with the results. On convalescent patients with bee venom (bee venom at the ratio of 1: 2000 dissolved in oil or almond oil peach) subcutaneous injection (bee venom injection KF), various arthritis 90% effective.

Wong Kin in apitherapy News Russia said apitherapy is strange. Also said Russia apitherapy clinics of Gregory •-Dahdouh is an 80-doctor, he said: "we are talking about the ' actual ' bee venom therapy is an ancient tradition of Russia. Is acupuncture and the combination of intermediary therapy, acupuncture role and the role of bee venom. In many areas we have achieved results in the treatment of low back pain by, nerve root inflammation, rheumatism, effect on.　　"By the bee venom of foreign information visible in the treatment of rheumatism and RA are special effects, its mechanism is relatively clear. 1. anti-inflammatory analgesic. Lorenzo Lorenzetti (C • J • Lorenzetti, 1 972 year), Chu Lille (r.b.zurler, 1973) and Zhang (y.h.chang, 1979) and other tests have confirmed that bee venom on Corrigent medicine will arthritis model has a significant anti-inflammatory activity. OLAF enquiries Grove (R • Ovcharov, 1976) reported that bee venom peptides can inhibit s a HT and dextran-induced inflammatory edema, also can inhibit Croton induced exudative inflammation. View bee venom that peptides and anti-inflammatory effects and it's a 5-hydroxytryptamine activity. Than Lin (1973), confirmed to 0.2 — 1 mg/kg dose subcutaneous or intravenous injection of a peptide, MCD on rat intra-articular injection of turpentine or sole injection of carrageenan-induced inflammation swelling are marked inhibition. The effect of strength ratio equal doses of anti-inflammatory effect of pine 100 times stronger. MCD a peptide while stimulating the pituitary-adrenal system, adrenalectomy is not fully discharged MCD a peptide and anti-inflammatory effects.　　Their anti-inflammatory effects may reduce capillary permeability, blocking leukocyte migration and inhibition of prostaglandin E2 synthesis of functions. Comfort level is 80 's from bee venom in new separate an anti-inflammatory peptides. Animal testing has shown that on the hind foot angle and vegetable gum edema and prostaglandin E edema have strong anti-inflammatory effect, so sick flattening is also a kind of prostaglandin E pharmacological antagonists.　　This intensive flattening on edema model and anti-inflammatory effects is not affected by the impact of adrenal resection. Bee venom is used to treat rheumatoid arthritis has a long history. Over the years on bee venom anti-inflammatory effect of active ingredients and its mechanism research of course people. Experimental studies have proven that bee venom on injection of formaldehyde, egg, fish and vegetable gum, Croton caused by rats arthritis, significantly on the role of prevention and treatment. All bee venom, bee venom peptides, bee venom that peptides, MCD a peptide can stimulate the pituitary-adrenal system, increase the cortical hormone release and have anti-inflammatory effects. Melittin also inhibits the blood's transitional, thus inhibiting the partial

Inflammatory response. Bee venom contains norepinephrine and dopamine, these Catecholamines also has anti-inflammatory activity.　　Bee venom on anti-inflammatory analgesic and its contents is its treatment of rheumatism and rheumatic illnesses-activity. 2. adjust the immunity levels. Bee venom on immunity levels have a two-way effect, in a certain dose and time enhances immune function, in other cases, and immunosuppression. Research shows that bee venom with immunosuppressive, active ingredients to low molecular weight compounds (molecular weight < 12000 — 15000).　　Bee venom and its component melittin, bee venom that peptides and MCD a peptide immune inhibitory effect was due to the stimulation of the adrenal cortical hormone secretion increases. University Hospital high Collinson, in view of the cell from Ts bee venom therapy for rheumatoid role links, that T cells in the immune system to perform a specific cellular immune function and immune function. And Ts subsets in immune regulation play an important role. Many studies have proven that T cells reduce and reduce its functions, in particular, the reduction function Ts cells, in the pathogenesis of Rheumatoid, has an important significance. The author believes that the bee venom treatment of RA of role links to Ts cells. Bee venom stimulation organisms that cause cell immune response, as the dose increases, the body produces endurance. As a result of immune tolerance, suppresses immune injury and autoimmune diseases. Ts cells in immune tolerance plays an important role. In this way, through the rs cell function and number of adjustments, changes in the immune response, in a certain dose (10 bee) can increase the body's defense capabilities and stimulate antibody production. When increasing the dose of bee venom, on immune response disincentive.　　Bee venom through adjustable Ts cells play a role in improving immune. Hunan Zhang as advocated the use of acquired immunity to the treatment of rheumatoid arthritis. This class is a connective tissue disease, also an immune system disease. Can I use enhanced rheumatoid arthritis patients with acquired immune competence method to cure rheumatism? author after extensive clinical practice to get answered. Can. Bee products for patients with RA, the immune system of patients, acquired immune capability enhanced with great effect. Rheumatoid arthritis can use apitherapy cure, truth lies in this.

In sum, the bee venom treatment of rheumatism, Rheumatoid comparison mechanism. At the same time, also see bee venom therapy in the treatment of rheumatism, rheumatoid arthritis and other treatment methods outgo.

(Ii) the clinical use of bee venom

Bee venom can directly enter the stung by the body, also available through the method body, can also be used to enter bee venom injection intramuscular injection method of entering the body. 1. live stung acupuncture, Hainan apitherapy hospital Wang Meng Jun reports. I've also suffer from rheumatism and rheumatoid arthritis to remnant.　　Since 1960 start survive stung thorn treatment, treatment adherence, repeatedly over the years, won today's health. From 1962 onwards, the author takes away the honey-bee-chasing the spare time, you have to treat rheumatism and rheumatoid arthritis, psoriasis-arthritis, bursitis, athletes Chondromalacia of joint pain, rheumatism, muscle pain, sciatica, headache, neuralgia, Rheumatoid myocarditis and Scleroderma, 000, 1 000 passengers. Age minimum of 5 years of age, the maximum age of 70; the course of a minimum of a few months and a maximum of 20 years; minimum treatment time is 1-5 days, 3 with bee to dozens of unequal; maximum treatment period of 3 months (80), with the effect of bee 1800 only, reaches more than 85 per cent, with most patients reflects very well.　　The news topic, where the bee sting therapy of patients, physical fitness, back to health after few recurrence. Use live stung thorn treatment of rheumatism and rheumatoid arthritis, in recent years more domestic coverage, its treatment as a criterion, the treatments vary, so it is very difficult to achieve a uniform, this establishment to be normalized. Guangzhou Chen Shu-Jen in the treatment of rheumatoid arthritis in the southern common 56 cases, maximum age 82 years, the longest course of 25 years, effective 55 cases. Kunming City Hospital of pipe compliance Hui, chenlili reported bee-for the treatment of rheumatoid arthritis, rheumatoid arthritis, 36 cases. Maximum 75 years of age, the course up to 30 years, the meridian points, powder, straight spines, Sting sting and each treatment 10 days a week. Anhui to Shun reports per day 2 only bee starts to week increment 2 only, reaches 14 only maintain their level, only about 450 total. Jinzhou Zhang Hai Yan reported bee-treatment of rheumatic disease and rheumatoid arthritis 350 cases, 90% of the total effective. Shijiazhuang hcma000913 wing bee-for the treatment of rheumatoid arthritis in 76 91 per cent of total valid strings.　　Room filled with bee-treatment of various diseases 279 cases, of which 36 patients with rheumatoid arthritis, rheumatoid arthritis 1O cases, meridians, scattered, straight spines, Sting sting and ear, daily 5-10 bee, up to 20% of the total effective 92.5. Despite the various reports is different, but the bee for rheumatoid arthritis and rheumatoid arthritis are the obvious effect of the knot or smart.

2. sting sting and penetration. Shandong Xiang feicheng Wang FA plus coverage of bee-bee venom ionization treatment through 49 cases of rheumatoid arthritis. Electric ion import, positive and negative turn, every 30 minutes. The amount of daily Bee only 20 a 30. Total effective 95.9 per cent. Bee venom import application more prevalent, but separate application seems not very satisfactory, and Stung medicine also as you can.

3. bee sting with medicine, Chengdu apitherapy hospital charges via Europe reported that stung before treatment, the appropriate medication to relieve symptoms, and control of bee venom treatment effects, then decreasing or stopped and during treatment with medication if Royal Jelly to enhance immunity. In accepting the 276 patients in rheumatoid factor turned cloudy 28 cases. total effective 92.1 per cent. Follow-up of 2 years in a stable condition, showing effective though slowly, but the lasting effects, adverse reactions is low. Beijing apitherapy hospital Wang Meng-lin, XING YUI with bee pin and bee products combination in the treatment of rheumatism preparations, such rheumatic 68 cases, total effective 97.05 per cent, and clearly see serum immunoglobulins (IgG, IgA, IgM) to increase the rate of increase in the PCT of lymphocytes, plasma lipids, blood rheology

Improved. Hunan Li spectrum reports, bee-plus take South of acanthopanax senticosus herbal (30 grams per day) for the treatment of rheumatoid arthritis 35 cases, efficient 97 per cent. Henan Sun Feng Chao reports, bee-herbs in the treatment of rheumatoid arthritis, better than separate bee-healer.

4. the bee venom treatment on polio. Beijing apitherapy hospital Wang Meng-lin reported polio patients chronically low, recurrent inflammation, excessive physical Constitution, expend tixu commonness, have severe nutritional deficiency. Bee products, herbs, fruit juice preparation became rare supplements. Inflammation is the similarity of arthralgia, anti-inflammatory and a set of common biological agents, which has become a matter exclusively grams. Bee products treat polio has achieved significant results, and with economic, practical, simple, easy, easy features of the promotion. Apitherapy aims to enhance the body's own immune system, mobilize volunteers, and since the potential cure is a 100% benefit but no harm new medical law. Bee products medical taken from nature, a pollution-free, non-invasive, non-infected and Western organic combination of typical medical new branch. Bee product differentiation and postpartum generally take 3-5 weeks for the course of severity of long, heavy with bi-type, 10 to 20 weeks, some need more time. Kunming City Hospital of chenlili, Pan art GUI report bee-Meridian therapy for postpartum 110 cases. This method is acupuncture medicine and combination of bee venom treatment.

5. other bee venom treatment of bone and joint disorders. Black Dragon carry Jixian Hospital of Zhou Xue reported bee-and herbs in the treatment of cervical spondylosis 45 cases, efficient and 100%. Jinzhou Corning hospital cultivates reported bee venom injection for the treatment of cervical spondylosis 7 cases, after 45 times of treatment, the pain disappears, activities, functional recovery and healing. Tianjin Xiaobailou hospital reported jizhong Wei injection of bee venom treatment of local injection, 2 cases of cervical and lumbar spondylosis, after 3 months of treatment, the move to work as usual. Hubei diao yongren reports of bee-massag with herbs. Bee sting of not more than 20 per day, only to detoxifying herbal, oral tissue regeneration by four Yang Zhi BU-fire, and cold. A month of treatment to rehabilitation hospital of Liaoning apitherapy. Wang Yun-Joo reported bee venom therapy hyperosteogeny 50 cases, typically 8-10 weeks may be the more, the radiation-last 100% efficient checked. Each dosage 20, 7-a course of treatment. As a result, 2 cases of multiple rheumatic muscle pain in patients with four courses of treatment, cure, and follow-up for half a year without recurrence. Charges via Europe reported that stung with 15 cases, Flex styloid tenosynovitis stenosis. Flex styloid stenosis of tendon sheath for is a common method of surgical diseases, medical treatment, but many are a long course of treatment. This group of 15 patients have wrist flexion side pain, activities or oppression with reflex pain, thumb activities may be restricted, subcutaneous nodules, palpable as clenched foot flexion test is positive, the diagnosis as torsion styloid tenosynovitis stenosis. Mining sting sting, Sting sting once or depending on their local redness, every other day or every other 2, Sting sting once, Sting sting from little bee number has gradually increased, the number of daily bee in less than 7 only.　　Sting sting parts should be daylight is not in the same Department amount to bee venom is organized full absorption and play the role of good treatment. This group of cases stung therapy l a 3 days mostly small swelling phenomenon and Tickle, while local lesion is improved, pain-relief, increased mobility. The 7-15 times, symptoms after treatment, the pain disappeared basic elimination, wrist and finger joint activities freely, nodular disappear to recover.　　Each number with a bee is 30-85, with 1-year follow-up study found no recurrence. Guangzhou University of traditional Chinese medicine branch as Deng jinfeng bee-for the treatment of rheumatoid arthritis with a case of hyperthyroidism. Symmetry of arthritis in patients 10 years with palpitations, sweating, insomnia, and neck enlargement five years. The bee-treatment, daily 8 only bee, after 40 days of therapy, not only of rheumatoid joint symptoms improve, independent goiter walking, but is not obvious, and neck as usual, hyperthyroidism symptoms substantially improved. Zhu Kam Ming reported use of bee venom injection for the treatment of rheumatoid arthritis with Hashimoto's Thyroiditis. Thyroid swelling pain, dysfunction, coupled with joint pain, not the cold water. After 2 weeks of treatment of the symptoms of thyroid swelling subsided, relieve joint pain-free.

2. Royal Jelly

(I) Royal Jelly in the treatment of rheumatism and Rheumatoid disease mechanism 1. nourish a strong role. Shao Tsu reported that Royal Jelly contains approximately about 1O kind of essential vitamins B1, B2: B6, B12, niacin, Pantothenic acid, biotin, folic acid, etc. Vitamin B12, folic acid and Nicotinic Acid and growth of human and animal. Functional compounds and fat metabolism are indispensable.　　Therefore, the single from Royal Jelly multivitamin, to understand its function of nourishing and strong. 2. enhanced and joint activity. Beijing Han Chen DH ° Royal Jelly by preventing the degradation of the body, so, the old "youth", because it stimulates the mind stable recovery joint flexibility.　　Pure Royal Jelly maybe and gold the same weight, the treatment of arthritis have effect. 3. anti-inflammatory effect. Anti-inflammatory effect of royal jelly. Japan reported monthly intramuscular injection 40 mg for the treatment of arthritis in 27 cases, of which 20 cases effectively. China, someone with a daily oral 400 mg Royal Jelly, even the clothes 3-6 months for the treatment of arthritis, with a total of 28 cases, of which 20 cases effectively.　　The left fly fresh Royal Jelly was used in the treatment of chronic rheumatic arthritis 77 cases, the effect is to the best of the spine. Royal Jelly have long been used in clinical treatment of some stubborn problems. On rheumatoid arthritis have better efficacy, Royal Jelly capric acid strong sterilization capability, but whether it can replace all the anti-inflammatory components also be further explored.

(Ii) the effect of Royal Jelly Royal Jelly for the treatment of rheumatoid arthritis and osteoarthritis pain, both at home and abroad. Introduction to Lin Shi generous treatment of arthritis, said Royal Jelly on the Royal Jelly report of clinical treatment of arthritis. Near saw Japan Science and technology literature speed report (1990) report, Japan Oita County beekeeping Association of nearly knee just after the article, introduction to his own suffering from rheumatoid arthritis for 15 years, walking difficulties.　　After taking Royal Jelly, restore health. Past General literature many think that the amount is to be taken should be of Royal Jelly 0.5 grams, and nearly ten is the amount to be taken after 5-8 g.　　Thus, on the consumption of Royal Jelly uses and research continues to develop. There are also reports of Queen

Pulp by iontophoresis treatment of arthritis and joint pain, not only eliminate symptoms fast pain relief effect is good, but can improve and restore joint function. Wuhan Zhu Li introduced taking Royal Jelly makes joint and low back pain-relief, rheumatoid arthritis, and even clothing for 9 months of Royal Jelly, Rheumatoid physical symptoms symptoms disappear, the better.

III. other bee products

(A) honey honey can buzhong, life qushi, used for postpartum treatment is effective. Hunan Xiao Yue-Chi reported Semiliquidambar honey treatment of arthritis. Semiliquidambar-Araliaceae trees, scientific name tree parameter. Have rheumatism, and activating detumescence bulk deposition analgesic effect. 8 cases successively in the treatment of rheumatoid arthritis patients, except in case of not clear out the remaining 7 patients have been cured. Guizhou Yang Shi-Qing reported an egg, vinegar 150-180 g, 150 — 120 grams of honey, eggs into vinegar in bubble 2-3 days to eggshell foam soft degrees. Remove the eggs, a small, 14 3, those minutes 5-6. Every morning with egg solution 1 part into the boiling water, add honey 30 a 40 g, stirring well, fasting. Treatable chronic rheumatism, sciatica, elderly patients with rheumatic longterm more of arthritis, especially suitable for hot and humid. Light objectors 15 — 20 eggs to suit a 40 to 50 eggs, a certain cure effect.

(Ii) and the hive propolis propolis have anti-inflammatory analgesic, regulation of immune function. Lin Ying lung reported using 10% propolis tincture and infrared treatment of soft tissue injury 50 cases: cured 20 cases, produce 10 cases, improved 20 cases. Treatment did not find allergy and other adverse reactions. Also for the treatment of cervical osteoarthritis 30 cases, there are different degrees of HYPEROSTOSIS of cervical spine. With 10% propolis tincture for import for 30 minutes each time, continuous 10 treatment, cure 7 cases, improvement in 14 cases and produce 8 cases, the invalid one. And the control group than significant difference (P = 6.76 X2, < O.01).　　Tip propolis tincture with anti-inflammatory pain, improve local blood circulation. Beehive's chemical composition is complex, not only contain beeswax components, but also including resins, sleeves, pigment, tannins and sugars, organic acids and fatty acids or Glycoside and contains iron, calcium, copper, potassium, drilling and other trace elements. Thus, in the clinic, use the Beehive leaching in the treatment of rheumatoid arthritis with good results.

(Iii) pollen and honey bee larvae

Bee Pollen in the treatment of joint diseases reported fewer, Dalian blue Pui Wan explains: a 72-year-old man who is suffering from arthritis, occasionally eat pollen and a half months, the joint symptoms disappear, wind or rain pain also light, often to the spirit more abundantly abundant outdoor activities. Hangzhou Zhang song in Hangzhou 10 multiple Queen Bee of a medical unit in the treatment of various diseases of the larvae of clinical observation studies confirm Queen twin blade enables most of the swelling subside in patients with rheumatic arthritis, pain relief, reduced resistance to the "o". Queen Bee larvae can adjust the central nervous system, improve the body's functions, both spirits, increased appetite, increased strength, but also can soothe, improve sleep quality. Its products are a new type of nourishing the corroborative.

(1m1m responsible editor: wanghui)